Introduction
Systemic lupus erythematosus (SLE; lupus) is an autoimmune disease that
impacts public health, and in females between five to sixty-four years
is between the top 20 main causes of mortality (1). SLE manifestations
correlated with subsequent immune complex deposition and formation,
various autoantibodies, and other immune processes (2, 3). The
neurological manifestations are seen in the 25-95% of cases with SLE.
Common manifestations include psychosis, cognitive dysfunction, and
headache (4, 5). According to one research, most patients have active
lupus symptoms that precede transverse myelitis (TM); however, TM may be
the first manifestation of lupus (6). TM is a spinal cord inflammatory
condition that may present acutely or sub-acutely (7). It is an uncommon
condition with an incidence of approximately one to four new cases per
million individuals every year (8). TM is histologically defined by
immune cell infiltration of the spinal cord, with pathogenesis mediated
by various immunological pathways (9). We describe one such case in
which TM was the only presentation of SLE.