Statistical Analysis
The collected data were analyzed
using software statistical computer package SPSS version 24.0 (IBM
Corp., Armonk, NY, USA).
Continuous normally distributed
variables were expressed as mean ± SD. Continuous non-normally
distributed variables were expressed as median ± IQR. Student t-test was
used to determine the difference between the two groups of normally
distributed variables. Mann-Whitney U test and Wilcoxon signed-rank were
used to determine the difference between the two groups of non-normally
distributed variables. Categorical variables are presented as number and
percentage and were analyzed using the Chi-Square test or Fisher exact
test. After Kaplan-Meier analysis,
survival curves were compared using Log Rank test. Receiver Operating
Characteristics (ROC) was plotted as sensitivity on Y axis and
1-specificity on X axis. The significance level was set at p< 0.05.