3.2 Altered T-cell subset frequencies
in lymphoid
tissue
CD3+ T cells were subdivided into αβ T cells
(CD3+/ γδ TCR–) and γδ T cells
(CD3+/ γδ TCR–). αβ T cells in
domestic pigs showed decreases 5 dpi in blood, spleen, lung, and liver
with corresponding increased γδ T-cell frequencies (Figure 1A, B). The
T-cell frequencies in domestic pigs returned to control levels 10 dpi,
except for αβ T-cell increases in the liver (Figure 1A). In wild boar,
we detected temporarily increased αβ T-cell frequencies in blood and
spleen 4 dpi but no other changes to baseline level (Figure 1A) and
largely unaffected γδ T-cell frequencies over the study period, except
for corresponding decreases in γδ T-cell frequencies in blood and spleen
(Figure 1B). No changes were detected in the gastro-hepatic lymph nodes
(ghLN, Lymphonodi hepatici or gastrici ) of both
subspecies.