3.6 Regulatory T cells were induced in both subspecies

FoxP3+ cells among CD4+/CD8α and CD4+/CD8α+ T cells were analyzed to identify regulatory T-cell responses . In spleen, lung, and ghLN, Treg frequencies increased significantly 7 or 10 dpi in domestic pigs and wild boar, with the highest frequencies in the lungs of both subspecies (Figure 7). Interestingly, although Tregs were induced earlier in domestic pigs, Treg frequencies reached higher levels in wild boar. Of note, there were more DP Tregs than CD4+/CD8α Tregs in both subspecies (Figure 7).