3.6 Regulatory T cells were induced in
both
subspecies
FoxP3+ cells among
CD4+/CD8α– and
CD4+/CD8α+ T cells were analyzed to
identify regulatory T-cell responses . In spleen, lung, and ghLN, Treg
frequencies increased significantly 7 or 10 dpi in domestic pigs and
wild boar, with the highest frequencies in the lungs of both subspecies
(Figure 7). Interestingly, although Tregs were induced earlier in
domestic pigs, Treg frequencies reached higher levels in wild boar. Of
note, there were more DP Tregs than
CD4+/CD8α– Tregs in both subspecies
(Figure 7).