Introduction
Anxiety and distress caused by the coronavirus disease 2019 (COVID-19) pandemic and preventative measures including social distancing seem to increase psychosocial stress in general populations.1, 2 Because children with cancer are vulnerable and they and their caregivers often already experience high levels of stress and anxiety,3 they may be affected in particular.4, 5 To extend the very limited available knowledge,2, 6 we aim to compare psychosocial functioning of Dutch children with cancer and their caregivers in the first months of the COVID-19 era to the pre-COVID-19 era.