Results
Roughly 75% of the regularly proposed psychosocial monitoring and screening questionnaires in clinical care were completed between January and end of May. Informed consent for research purposes was provided for 87% of the children-reported outcomes and 94% of the caregiver-reported outcomes. Finally, 799 (caregivers of) children with cancer (pre-COVID-19/COVID-19 era: n=494/438, 17% in both era) participated in this study. Because of differences in assessment frequency and respondents, samples differed per outcome (see Table 1 for characteristics).
Results on HRQoL and fatigue of children with cancer in outpatient care and caregiver distress in the pre-COVID-19 and COVID-19 era are presented in Table 2. A smaller percentage of caregivers showed clinical distress in the COVID-19 era on the DT-P compared to the pre-COVID-19 era (OR [CI]: 0.59 [0.42; 0.83], p=0.002). No other statistically significant differences or effect modification for treatment status were found.