Treatment Applications
The clinical treatment trial was conducted on ‘fresh’ FMD lesions,
containing intact vesicles or recently ruptured vesicles. Animals
treated with TS had lesions liberally sprayed with 2ml of the product,
as per label instructions. Animals treated with MO received an
intra-muscular injection of the product, also at doses per label
instructions. Clinical response observations were noted, including any
improvements in capacity and ability of the animal to walk and eat. The
following semi-quantitative clinical measurements were made:
Lesion healing score (LHS) on a scale of 1 to 4 (adapted from Al-Lethie
et al., 2018)
Appetite score (AS) on a scale of 1 to 4 (from Al-Lethie et al., 2018)
Lesion size (cm): healing of lesions was measured quantitatively in the
field using a 30-cm ruler, every 3 days from day zero (D0) through day
15 (D15), with lesions photographed using android mobile phones.