Treatment Applications
The clinical treatment trial was conducted on ‘fresh’ FMD lesions, containing intact vesicles or recently ruptured vesicles. Animals treated with TS had lesions liberally sprayed with 2ml of the product, as per label instructions. Animals treated with MO received an intra-muscular injection of the product, also at doses per label instructions. Clinical response observations were noted, including any improvements in capacity and ability of the animal to walk and eat. The following semi-quantitative clinical measurements were made:
Lesion healing score (LHS) on a scale of 1 to 4 (adapted from Al-Lethie et al., 2018)
Appetite score (AS) on a scale of 1 to 4 (from Al-Lethie et al., 2018)
Lesion size (cm): healing of lesions was measured quantitatively in the field using a 30-cm ruler, every 3 days from day zero (D0) through day 15 (D15), with lesions photographed using android mobile phones.