Title: Altered hippocampal kynurenine pathway metabolism
contribute to hyperexcitability in mesial temporal lobe
epilepsy-hippocampal sclerosis
Running title: Altered kynurenine pathway metabolism in
hippocampal sclerosis
Authors: Soumil Dey1, Aparna Banerjee
Dixit2, Manjari Tripathi3, Ramesh S.
Doddamani1, Meher C. Sharma4,
Sanjeev Lalwani5, P. Sarat
Chandra1*, Jyotirmoy Banerjee6*
1 Department of Neurosurgery, All India Institute of Medical Sciences,
New Delhi, India
2 Dr. B. R. Ambedkar Centre for Biomedical Research, University of
Delhi, New Delhi, India
3 Department of Neurology, All India Institute of Medical Sciences, New
Delhi, India
4 Department of Pathology, All India Institute of Medical Sciences, New
Delhi, India
5 Department of Forensic Medicine and Toxicology, All India Institute of
Medical Sciences, New Delhi, India
6 Department of Biophysics, All India Institute of Medical Sciences, New
Delhi, India
*Corresponding author
Jyotirmoy Banerjee
Department of Biophysics
All India Institute of Medical Sciences (AIIMS), New Delhi, India-110029
Telephone: +91-11-26549321, Email:
jyotirmoybanerjee1@gmail.com
P Sarat Chandra
Department of Neurosurgery
All India Institute of Medical Sciences (AIIMS), New Delhi, India.
110029.
Telephone: +91-11-26546477, E-mail:
saratpchandra3@gmail.com