What is already known about this subject?
- Unfractionated heparin (UFH) has antiviral properties against
SARS-CoV-2 at therapeutically relevant concentrations, as well as
anti-inflammatory and anticoagulant effects.
- Inhaled nebulised UFH has shown to improve outcomes in pre-pandemic
experimental and clinical studies of acute lung injury and ARDS.
- There is a strong scientific rationale for urgent investigation of the
therapeutic potential of inhaled nebulised UFH for COVID-19.