Title: Comparison of the predictive value of area under the
curve versus maximum serum concentration of intravenous tobramycin in
cystic fibrosis patients treated for an acute pulmonary exacerbation
Katherine B. Landmesser1, PharmD; Elizabeth B.
Autry1,2, PharmD; Brian M.
Gardner1,2, PharmD; Katherine A.
Bosko2; Aric Schadler2, PhD; Robert
J. Kuhn, PharmD1,2
1 Department of Pharmacy, Kentucky Children’s
Hospital, Lexington, Kentucky; 2 Department of
Pharmacy, The University of Kentucky College of Pharmacy, Lexington, KY
Acknowledgments: Alexa Baskin
Research institution: University of Kentucky HealthCare
Running head: Pharmacokinetic analysis of IV tobramycin in CF
Keywords: Antibiotic therapy, cystic fibrosis,
pharmacodynamics, pharmacokinetics, tobramycin