3.3-Subgroup analyses by age
Respiratory syncytial virus and HRV (except for between 25-60 months)
coinfections with any virus were independently associated with severe
disease in all age groups (Figure 3-5, Supplemental Figure S1, S2).
While children between 4-24 months had a higher risk of severe infection
related to PIV3 coinfection (Figure 3-5, Supplemental Figure S1), those
between 7-12 months and 25-60 months had severe illness associated with
influenza A coinfection (Figure 5, Supplemental Figure S2). Besides,
HBoV coinfection was independently a risk factor for severe disease in
children between 7-12 months (Figure 5). Unfortunately, we did not
analyze the subgroup analysis for EV coinfection because of its small
sample size.