3.3-Subgroup analyses by age
Respiratory syncytial virus and HRV (except for between 25-60 months) coinfections with any virus were independently associated with severe disease in all age groups (Figure 3-5, Supplemental Figure S1, S2). While children between 4-24 months had a higher risk of severe infection related to PIV3 coinfection (Figure 3-5, Supplemental Figure S1), those between 7-12 months and 25-60 months had severe illness associated with influenza A coinfection (Figure 5, Supplemental Figure S2). Besides, HBoV coinfection was independently a risk factor for severe disease in children between 7-12 months (Figure 5). Unfortunately, we did not analyze the subgroup analysis for EV coinfection because of its small sample size.