Figure legends
Fig. 1. (A) Photograph taken during the patient’s initial
visit, showing an ulcerative lesion measuring ∼22 mm in diameter on the
right tongue margin. (B) MR image showing frontal disconnection. (C) MR
image in the horizontal view. An invasive lesion showing a contrast
effect with gadolinium was observed on the right tongue margin. (D) A
PET scan image showing high accumulation of fluorodeoxyglucose in the
right tongue margin.
Fig. 2. (A) MR image taken seven months after tongue cancer
surgery. The right upper internal jugular vein lymph node had become
swollen with a minor axis of ∼12 mm, and the T2-emphasized image shows a
region with moderate signal intensity that included a part of the
low-signal region. (B) A CT scan image taken three months after right
neck dissection. The right submandibular lymph node had become swollen
with a minor axis of ∼15 mm, and the boundary with the surrounding area
was unclear. (C) A CT scan image taken after chemoradiotherapy.
No change in the size of the
right submandibular lymph node was observed, and the boundary with the
surrounding area was unclear.
Fig. 3. (A) A CT scan image taken after three courses of
cetuximab combination chemotherapy. The right submandibular recurrent
lymph node had disappeared. (B) A CT scan image taken three months after
maintenance administration of cetuximab alone was initiated. Swelling of
the right submandibular lymph node was observed. (C) A CT scan image
taken after six doses of nivolumab. Shrinkage of the right submandibular
lymph node was observed. (D) ACT scan image taken after 14 doses of
nivolumab. Significant enlargement of the right submandibular lymph node
was observed. (E) A CT scan image taken after three courses of
chemotherapy with cetuximab. Significant reduction of the right
submandibular recurrent lymph node was observed. (F) A CT scan image
taken after 52 doses of cetuximab alone. The right submandibular lymph
node had disappeared.
Fig. 4. (A, B) PET scan images taken 20 months after CR was
achieved. No recurrence or metastasis was observed.