LIMITATIONS.
Our study was an analysis from clinical database, from single referral center with limited number of patients and cardiovascular events. Diastolic parameters are difficult to assess in valvular patients with volume overload; however, they have been analyzed in other volume overload valvulopathies, such as mitral regurgitation, with confirmed prognostic value. Due to the retrospective nature of the study, LA auto-strain was not available throughout the sample. Thus, further prospective studies are required to validate our findings.