1 | INTRODUCTION
Since the World Health Organization (WHO) declared the Covid-19 pandemic, it has spread rapidly in more than 200 countries. The Covid-19 pandemic in the globe was far more severe than the 2003 SARS in China due to transmission in multiple ways. So far (April 5, 2022), there were more than 489.77 million confirmed cases and over 6.15 million deaths in countries worldwide. And these data are still climbing since there are more emerging coronavirus variants (Table 1), which include Delta and Omicron with more transmissible, infectious, and severe. Hence, the SARS-CoV-2 and its variants are the strong “enemy” of humankind. It can be said that “active Covid-19, painful world”. Then, how to effectively fight against coronavirus and Covid-19? Are there some reliable “antidotes”? How to do better cardiovascular protection and prevention during the pandemic and post-Covid-19 era?