CONCLUSIONS
Since unhealthy E(e)SEEDi lifestyle links to the new origins and novel
mechanisms of fCVD, the author setup a fresh theory, that is, the
“brain-heart-gut” axis. The novel mechanisms of fCVD are mediated by
the role of “environment-sleep-emotion-exercise-diet” and the gut
microbiota in early life, which is like a “Golden Hoop Curse”. On the
one hand, the “brain-heart-gut” axis provides a theoretical basis not
only for the cardiovascular health benefits of “keeping the pubic
region” advocated by traditional Chinese medicine, but also for the
control and prevention of both eCVD and fCVD; On the other hand,
“keeping the pubic region” is the best example on the fresh theory of
“brain-heart-gut” axis. As a new theory, the “brain-heart-gut” axis
will help us to earlier and better prevent and control both eCVD and
fCVD with healthy E(e)SEEDi lifestyle.