Sample Size
Of the 5000 deliveries per year at AKUH, approximately 12% (600) are admitted to the NICU and approximately 70% (420) of these require intubation. Using a conservative rate of 5% for esophageal intubation, the sample size was calculated for the primary outcome using a two-sided equivalence test for correlated proportions. To achieve 80% power at a 5% significance level, a total of 222 participants were needed for the primary outcome. Details of the secondary and tertiary outcome sample size calculations are available in the protocol paper.23