Abstract and keywords
Background: Numerous guidelines have been published for atopic
dermatitis management in children in recent years. To date, the quality
of the newest guidelines has not been appraised.
Objective: To identify and evaluate guidelines for the
management of atopic dermatitis in children.
Design: A review of the guidelines for the management of atopic
dermatitis in children and quality appraisal with
AGREE
II was conducted.
Methods: We reviewed literature retrieved from PubMed, Web of
Science, Ovid, ScienceDirect, Embase, China National Knowledge
Infrastructure, WanFang Data, and guidelines websites. Search period
from 1 January 2016 to 31
December
2021. The following keywords were used for searching: ‘atopic
dermatitis’, ‘atopic eczema’, ‘eczema’, ‘guideline’ and ‘consensus’. The
quality of the guidelines was assessed by two assessors using the
Appraisal of Guidelines for Research & Evaluation II (AGREE II)
instrument independently, and domain scores were considered of
sufficient quality when > 60%. Guidelines recommendations
were reviewed.
Results: Nineteen guidelines were included in the study. Three
guidelines were graded A level that recommended for use in practice.
Eleven guidelines were graded B level that recommended for use in
revision. The remaining five guidelines were rated C level not as
recommended. The average score of six domains of AGREE II was 64.76%,
48.53%, 42.35%, 73.83%, 32.23% and 70.17%, respectively. The
consistency test showed that ICC ranged from 0.497 (95%CI: 0.105,
0.705) to 0.970 (95%CI: 0.93, 0.987) in the results of two assessors’
tests of the guidelines.
Conclusions:Most
guidelines were recommended for use with revision in the study. No major
changes in primary management of atopic dermatitis in children compared
to previous evidence. New biologic agents and complementary alternative
medicine were increasingly available, but evidence for the treatment of
atopic dermatitis in children was still limited.
Keywords: Dermatitis, Atopic; Eczema; Child; Guideline