3. Data collection and follow-up
Before treatment: pelvic magnetic resonance imaging (MRI) and US
examination were performed to record the position and volume of the
uterus, and the number, location and volume of UFs. On the basis of FIGO
classification[10, 11] , according to the
relationship between UFs and
myometrium, endometrium and serous layer, UFs were classified into
submucosal fibroids, intramural fibroids and subserosal
fibroids[10]. The patient’s age,
body mass index, marital status,
fertility history (pregnancy and parity, history of spontaneous
abortion, history of induced abortion, history of spontaneous delivery,
history of caesarean section and history of assisted reproduction and
future fertility plan) were recorded. All patients completed uterine
fibroid symptoms and health-related quality of life (UFS-QOL) score to
evaluate symptom severity scale (SSS) and health-related quality of life
score (HQOL).
After treatment: the ablation rate of UFs was evaluated by enhanced MRI
within 3 days; the volume of uterus and UFs were evaluated by US 3, 6, 9
and 12 months after MWA, and the reduction rate of uterus and UFs were
calculated. The time and mode of conception, pregnancy outcome and
perinatal adverse events were followed up. According to the follow-up
results, the patients were divided into pregnancy group and
non-pregnancy group.