Bullet point summary:
What is already known?
GAG therapy are widely used for the treatment of BPS/IC and other inflammatory bladder conditions.
The aim of GAG-therapy is to improve barrier function and recover the chronically damaged urothelium.
What this study adds:
The effect of CS-replenishment therapy on barrier recovery in a chronic damaged setting.
Clinical significance:
BPS/IC is a chronic condition of the bladder, this study will add evidence for GAG-therapy.