Mean (SD) DMT concentration (ng/ml) SPL026 9 mga (n=5) SPL026 12 mga (n=6) SPL026 17 mga (n=5) SPL026 21.5 mga (n=6)
Pre-dose 0 0 0 0
2 min 1.95 (1.57) 5.41 (1.80) 7.01 (11.75) 4.32 (2.88)
5 min 10.01 (7.01) 13.47 (3.29) 18.25 (16.57) 13.20 (5.65)
6 min 11.98 (8.69) 21.63 (18.63) 25.48 (23.75) 17.53 (5.59)
7 min 15.86 (13.24) 23.63 (19.55) 37.43 (37.13) 25.73 (8.32)
Immediately before infusion termination 16.27 (11.78) 26.05 (14.72) 62.28 (41.16) 62.20 (26.52)
11 min 17.47 (10.63) 23.14 (11.85) 62.80 (46.10) 53.03 (16.91)
13 min 14.22 (8.17) 20.50 (8.94) 22.55 (9.12) 40.85 (14.51)
15 min 7.77 (4.46) 16.73 (7.89) 18.30 (8.63) 30.23 (9.80)
30 min 7.02 (8.72) 3.78 (3.62) 3.68 (2.95) 9.50 (5.65)
60 min 0.43 (0.33) 0.65 (0.90) 0.49 (0.54) 1.19 (0.76)
120 min 0.05 (0.05) 0.06 (0.14) 0.05 (0.07) 0.09 (0.08)
240 min 0 0 0 0.05 (0.12)