FIGURE 1. Aberrant overexpression of UHRF1 in PCa tissues and promoted PCa progression. a Comparison of UHRF1 mRNA levels in PCa (n=481) and normal tissues (n=51). b Comparison of UHRF1 mRNA levels in different TNM stage groups of PCa. c Colony-formation assays, histogram and statistics indicated the number of colonies per 500 plated cells. Data are representative of three independent experiments and values are expressed in mean ± SD. Significance was determined by Student’s t-test, **p < 0.01.d ROC curve was used to verify the diagnostic value of UHRF1 overexpression for PCa. e Recurrence free survival analysis for high (red) and low (blue) expression of UHRF1 in PCa samples from TCGA.