Introduction
Cryptosporidium causes watery diarrhea, despite the normal population it might prolonged and life threatening in severely immunocompromised individuals(1). The enterocytes of the small intestine are the main place of the parasite development followed by villus atrophy and crypt hyperplasia in immunocompromised patients(2). In the current study, we reported Cryptosporidium gastroduodenitis in 17 years old female with HIV (human immunodeficiency virus).