Methods
This systematic review was conducted and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines 13 and has been registered in PROSPERO (registration no. CRD42022310121). The PRISMA checklists were available in Supplementary Materials Table S1.
We conducted a systematic search of PubMed, Embase, the Cochrane Library, Sinomed, China National Knowledge Infrastructure, and Wanfang Data from inception through February 15th, 2022, using a combination of MeSH terms, Emtree headings, and keywords: stroke, Anti-Bacterial Agents, antibiotic prophylaxis, and infections. In addition, a hand search of the reference lists of relevant reviews was performed to identify potential studies. We obtained data from the author or published meta-analysis for any missing or unpublished data. The full search strategy was presented in Supplementary Materials Table S2.