ABSTRACT
Hantaviridae currently encompasses seven genera and 54 species.
Multiple hantaviruses, such as Hantaan virus , Seoul virus ,Dobrava-Belgrade virus , Puumala virus , Andes virus ,
and Sin Nombre virus , are highly pathogenic to humans. They cause
hemorrhagic fever with renal syndrome (HFRS) and hantavirus
cardiopulmonary syndrome or hantavirus pulmonary syndrome (HCPS/HPS) in
many countries.
Some
hantaviruses infect wild or domestic animals without causing severe
symptoms. Rodents, shrews, and bats are reservoirs of various mammalian
hantaviruses. Studies on the genomics, taxonomy, evolution, replication,
transmission, pathogenicity, and control of hantaviruses, as well as
patient treatment, have made significant advances in recent years.
Meanwhile, novel hantaviruses infecting bats, rodents, shrews,
amphibians, and fish have been identified. This systematic review
compiles these advancements to aid researchers and the public in better
recognizing this zoonotic virus family with global public health
significance.