6. Replication of hantaviruses
The replication processes of hantaviruses in host cells include
attachment to host cells and internalization, membrane fusion, transport
and release into the cytoplasm, transcription, replication, translation
of the genome, and assembly and release of the virion (Figure4 ).60 Vascular endothelial cells and
macrophages are the primary sites of hantavirus
replication.61