Author (year) Study design Number of patients Age Patient population Study variables
(socio-economic status, insurance type, ethnicity, environment, sex) Primary and secondary outcome variables
Bratton et al., (2002) Retrospective cohort study 1333 <18 years Children with a primary diagnosis of asthma admitted to one of 14 PICU’s in the U.S.A. Insurance type (commercial, health maintenance organization, Medicaid, self-pay or ‘other’) PICU LOS, hospital LOS, duration of mechanical ventilation, PRISM-III score
Epstein et al., (2014) Retrospective observational study 5390 1-12 years Children with a primary respiratory diagnosis admitted to the PICU in the U.S.A. Ethnicity, neighborhood’s ethnicity and median income, insurance type PIM2-score, mortality
Files et al., (2009) Retrospective chart review 125 <18 years Children with asthma admitted to the PICU in the U.S.A. Ethnicity Need for PICU admission, mechanical ventilation
Frigyesi et al., (2017) Prospective observational study 21972 <18 years Children with a respiratory insufficiency admitted to the PICU in Sweden Sex PICU LOS, mortality
Hardelid et al., (2018) Retrospective data analysis 1961 < 16 years Children with an influenza infection admitted to the PICU in England Ethnicity, socio-economic status Mortality, type of ventilation
Jroundi et al., (2019) Retrospective cohort study 13501 2-17 years Children from four states in the U.S.A. hospitalized for asthma with a prior asthma-related admission to a PICU Ethnicity, median household income for the state, type of medical insurance Asthma-related readmission
Leimanis Laurens et al., (2020)
Retrospective chart review
187
<5 months
Infants admitted to the PICU in the U.S.A. with a severe respiratory illness
Diet (breastfed, formula fed), insurance status, median household income (from zip code)
PICU LOS, readmission, mortality
Mukherjee et al., (2022) Prospective observational study 2195 <14 years Children with asthma admitted to the PICU in England Socio-economic status (English Index of Multiple Deprivations categorized in domains of income, employment, health, education, housing, crime and living environment) PIM2-score, mechanical ventilation, PICU LOS, survival
O’Donnell et al., (2010) Prospective observational study 4641 <1 year Infants with an acute respiratory failure admitted to the PICU in England or Wales Ethnicity Mortality
Rodriguez-Martinez et al., (2022) Cross-sectional cohort study 1215 <5 years Children with an infection with RSV admitted to the PICU in Colombia Ethnicity, socioeconomic stratum (high, middle and low based on socioeconomic factors, such as income, employment, housing, and education), type of health insurance coverage Respiratory failure (need for (non)-invasive ventilatory support), need for PICU admission, mortality
Sala et al., (2011) Retrospective data analysis 3318 <18 years Children with asthma admitted to the PICU with respiratory failure in the U.S.A. Ethnicity PICU LOS, PIM2-score, PRISM-III score, respiratory failure (mechanical ventilation)
Samir et al., (2011) Retrospective study 230 2-11 years Children with asthma admitted to a PICU in Canada ETS PICU LOS, clinical asthma score
Silber et al., (2017) Multivariate matched cohort design 11079 3-18 years Children with asthma admitted to the PICU in the U.S.A. Ethnicity, medical insurance type PICU LOS, need for PICU admission
Slain et al., (2018) Single-center retrospective study 145 2-11 months Infants with a bronchiolitis admitted to the PICU in the U.S.A. Median household income, ethnicity PICU LOS, hospital LOS, PIM2-score, mechanical ventilation
Swathi et al., (2021) Prospective observational study 2793 2 months-5 years Children and infants with an acute respiratory disease admitted to the PICU in India Breastfeeding practices (diet), socioeconomic class as per modified Kuppuswamy scale Hospital LOS, need for PICU admission, mechanical ventilation, mortality