2.4. Data Extraction and Quality Assessment
Data from eligible studies included in the analysis were extracted by two independent researchers (Z.Y.Z and F.L), and any potential disagreements were resolved by a third researcher (R.X.W). The extracted data mainly includes: title, first author, publication year, study design, sample size, follow-up time, LAAO device, Pre-procedure imaging and ICE Location. Meanwhile we also extracted relevant clinical outcomes, including: acute procedural success, total procedural time, Fluoroscopic time, Contrast volume, short-term complications and long-term complications.
Two independent researchers (Z.Y.Z and J.Z) evaluated study quality by two appraisal tools. The Newcastle-Ottawa Quality Assessment Scale was used to evaluated the two-arm observation [4]. The Institute of Health Economics checklist was used for the single-arm study[5]. Any disagreements were discussed and resolved by consulting a third researcher (R.X.W).