3.2.2 Pooled rate of procedural success in ICE group
A total of 20 eligible studies (1,564 patients undergoing LAAO with ICE procedural guidance) reported the rate of procedural success in ICE Group[6-15] . The pooled rate of procedural success was 0.99 (95% CI: 0.98–1.0; P = 0.02; I² = 43.69%) with the random-effect model (Figure 4 ). Meanwhile we performed a subgroup analysis with eight subgroup factors for procedural success in ICE group, and the results are shown in Table 2 . Overall, the pooled rate of procedural success in ICE Group does not differ significantly between subgroups.
Also, sensitivity analysis showed that no significant change was detected in the overall combined proportion, ranging from 0.98 (95% CI: 0.97, 0.99) to 0.99 (95% CI: 0.98,1.00), indicating that no single study dominated the combined proportion and heterogeneity. Moreover, Egger’s test was performed and result showed no publication bias (P =0.068). which indicated that the results were considered to be robust.