Two trials reported the inclusion of patients
with acute poisoning within 6 hours of AlP exposure (39) (41), one
within 2.5 hours (40), and one within 2 hours (42). Although one of
these (40) would enroll patients within 2.5 hours post-exposure, all
participants consulted before 2 hours, so we pooled these results with
the most recent trial (42). Treating these trials as a subgroup of the
main analysis (analysis 1.1, outcome 1: Mortality) the pooled analysis
at the latency from exposure to AlP fewer or equal to 2 hs delivers an
RR of 0.74 (95% CI 0.53 to 1.02; participants = 102) with a low level
of heterogeneity (Figure 6 : Forest plot of subgroup analysis:
latency from exposure to AlP). The remaining trials (39) (41), with
those patients who arrived more than 2 hours after AlP exposure,
delivered a RR of 0.50 (95% CI 0.34 to 0.74; participants = 124;
I2 = 0%).