Although GL is a treatment that has been used for more than 200 years in the management of acute poisoning, there is low certainty of its benefit (29). Some authors recommend that must be performed within the first 30-60 minutes after ingestion, in massive intake of highly lethal xenobiotics with no effective specific antidote or alternative therapies (e.g., hemodialysis). Nevertheless, due to evidence of persistence of significant amounts of xenobiotics in the stomach after 60 minutes post-ingestion, some other authors recommend GL in patients up to 6 hours after ingestion (30).