Two trials reported the inclusion of patients with acute poisoning within 6 hours of AlP exposure (39) (41), one within 2.5 hours (40), and one within 2 hours (42). Although one of these (40) would enroll patients within 2.5 hours post-exposure, all participants consulted before 2 hours, so we pooled these results with the most recent trial (42). Treating these trials as a subgroup of the main analysis (analysis 1.1, outcome 1: Mortality) the pooled analysis at the latency from exposure to AlP fewer or equal to 2 hs delivers an RR of 0.74 (95% CI 0.53 to 1.02; participants = 102) with a low level of heterogeneity (Figure 6 : Forest plot of subgroup analysis: latency from exposure to AlP). The remaining trials (39) (41), with those patients who arrived more than 2 hours after AlP exposure, delivered a RR of 0.50 (95% CI 0.34 to 0.74; participants = 124; I2 = 0%).