Three trials (37)(38)(43) reported the inclusion of patients with latency from AlP exposure greater than 2 hours. Pooling the results as a subgroup of the main analysis (analysis 2.1, outcome 1: Mortality) presents an RR of 0.78 (95% CI of 0.64 to 0.96; participants = 172; I2 = 0%) shown inFigure 12 . Once again, the only trial (42) that included patients within 2 hours of latency is the one with the lowest risk of bias and found no statistically significant differences in mortality between the two groups.