Selection of studies. Data extraction was done using a predefined electronic form including study characteristics, details of participants, interventions, comparators, and outcomes. The results were filtered by RCT using the following filter provided by the Cochrane Handbook for Systematic Reviews (35): ((randomized controlled trial [pt] OR controlled clinical trial [pt] OR randomized [tiab] OR placebo [tiab] OR clinical trials as topic [mesh: noexp] OR randomly [tiab] OR trial [ti]) NOT (animals [mh] NOT humans [mh]).