CONCLUSIONS
Implications for practice
Limited evidence suggests that GL with paraffin oil is
effective in reducing the mortality rate in acute AlP poisoning, showing
a relative risk reduction of 38% compared with standard treatment.
Likewise, limited evidence showed a relative risk reduction of 38% in
favor of paraffin oil concerning the need for intubation and mechanical
ventilation. This efficacy was not confirmed in terms of length of
hospital stay or the total amount of vasoactive agents
used
Very limited evidence suggests that GL with coconut oil may
have benefits in terms of mortality in patients with acute AlP
poisoning. However, current evidence does not confirm these benefits
about the need for mechanical ventilation, hospital length, or
vasopressor
requirements.
Very limited evidence suggests that both interventions would
have a benign safety profile. However, only one trial reported AEs as a
predefined outcome, these being gastrointestinal, mild, and
transient.
Implications for research