CONCLUSIONS

Implications for practice

Limited evidence suggests that GL with paraffin oil is effective in reducing the mortality rate in acute AlP poisoning, showing a relative risk reduction of 38% compared with standard treatment. Likewise, limited evidence showed a relative risk reduction of 38% in favor of paraffin oil concerning the need for intubation and mechanical ventilation. This efficacy was not confirmed in terms of length of hospital stay or the total amount of vasoactive agents used
Very limited evidence suggests that GL with coconut oil may have benefits in terms of mortality in patients with acute AlP poisoning. However, current evidence does not confirm these benefits about the need for mechanical ventilation, hospital length, or vasopressor requirements.
Very limited evidence suggests that both interventions would have a benign safety profile. However, only one trial reported AEs as a predefined outcome, these being gastrointestinal, mild, and transient.

Implications for research