Figure S1. Satellite culture from bioreactor production of AAV6
at medium cell density. Cells were transfected at 4 million cells per
mL (medium cell density, MCD), and plasmid DNA was delivered on a cell
basis (1 µg/106 cells). Time indicated as hours
post-transfection (hpt). A) Cell growth kinetics and viability. B)
Volumetric titer (VG/mL). C) Cell-specific viral yield (VG/cell). D)
Functional titer (ETU/mL). E) Ratio between volumetric and functional
titer (VG/ETU). n=1.