Statistical Analysis:
Data were analysed utilizing the IBM SPSS Statistics for Windows,
version 20.0 (IBM Corp., Armonk, N.Y., USA), for all statistical
analysis purposes. Data quality assurance measures were applied for data
completeness and accuracy and summary of statistics were obtained and
analysed as baseline and demographic characteristics were defined using
frequencies and percentages for categorical values and relevant
variables were cross-tabulated. While mean, median, range applied for
follow-up durations, in years. Survival analysis was performed utilizing
Kaplan-Meier method, to calculate 3-year overall survival of the cohort
as time from diagnosis date to the date last seen or date of death in
case of a deceased patient was used to calculate survival time (in
years), the difference between survivals were tested using either the
long-rank or Taron-Ware test as applicable, p-value of < 0.05
considered statistically significant.