2.4. Ethical statement
Institutional animal ethics committee, Dr Harisingh Gour Vishwavidyalaya, Sagar (M.P.) (A Central University) (Approval No.:379/CPCSEA/IAEC-2021/004), at Department of Pharmaceutical Sciences, provided its ethical endorsement. International standards were followed in the handling and usage of laboratory animals. The study was conducted in accordance with the Basic & Clinical Pharmacology & Toxicology policy for experimental and clinical studies.13