Figure 5 Effect of Nissl staining results on hippocampal CA1 area of SD rats in each group
Note: *P <0.05 and **P <0.01 compared with the CON+NS group; #P <0.05 and##P <0.01 compared with the MS+NS group.
3.2.2 Effect of probiotics on inflammatory factors in the serum of mother-infant separated offspring depression-like rats
The levels of IL-1β, IL-6, and TNF-α inflammatory factors in rat serum were detected by ELISA. the results of Elisa assay showed that the concentrations of IL-1β, IL-6, and TNF-α in serum of rats in MS+NS group were increased compared with CON+NS group, and the difference was statistically significant (P <0.01); after the intervention, compared with MS+NS group, the The concentrations of IL-1β, IL-6 and TNF-α in serum of rats in MS+P group decreased, and the difference was statistically significant (P <0.05); compared with MS+P group, there was no significant change in the expression levels of IL-1β, IL-6 and TNF-α in serum of SD rats in CON+NS group (P >0.05). Figure 6 (A, B, C).