3.3 Ferroptosis and hypertension
Hypertension is one of the risk factors for cardiovascular and cerebrovascular diseases such as atherosclerosis and ischemic stroke. Its pathophysiological mechanism is mainly related to increased vascular resistance, manifested by endothelial dysfunction, increased vasoconstriction, and arterial remodeling. In recent years, more and more studies have found that ferroptosis is closely related to the occurrence and development of hypertension7,89. Therefore, understanding the specific relationship between ferroptosis and hypertension will be of great benefit to the treatment of hypertension and the prevention of cerebrovascular disease complications caused by hypertension.