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TABLE 1 Features of pediatric primary central nervous system ALK+ALCL reported in the literature
FIGURE 1 A: MRI T2-weighted images, showing two isointense parasagittal lesions on the right falco-tentorial corner, surrounding by wide edema. B (axial), C-D (coronal): T1-weighted images with homogeneous contrast enhancement after Gadolinium administration.
FIGURE 2 A: Diffuse infiltration of large atypical T-cells (H-E, 100x). B: Higher power detail, showing hallmark T-cells with large bean-shaped nuclei (H-E, 200x). C: Diffuse immunopositivity for CD30 (200x). D: Immunoreactivity for EMA (200x).