CONCLUSION
In our case, the final diagnosis was a paraviral bullous skin eruption following a primary EBV infection.
In fact, the temporal association with an acute viraemic EBV infection and the progressive improvement of skin lesions with the resolution of the viraemia supported the hypothesis of a paraviral skin eruption.
On the other hand, the negativity of the direct immunofluorescence assay, the self-limiting course and the excellent response to small doses of systemic steroid did not support the hypothesis of an autoimmune bullous disease.
Further studies are needed in order to elucidate the association between EBV-infection and bullous eruption.
In clinical practice, in case of an acute skin bullous eruption the possible etiology of EBV-infection should be considered, also in pediatric age.