Title: Microproteins—Discovery, Structure, and Function
Authors: Jessica J. Mohsen1,2, Alina A.
Martel2, Sarah A. Slavoff1,2,3
- Department of Chemistry, Yale University, New Haven, CT, USA
- Institute of Biomolecular Design and Discovery, Yale University, West
Haven, CT, USA
- Department of Molecular Biophysics and Biochemistry, Yale University,
New Haven, CT, USA
Corresponding Author : Associate Professor of Chemistry Sarah A.
Slavoff1,2,3
sarah.slavoff@yale.edu
Yale University West Campus
Institute of Biomolecular Design and Discovery
Molecular Innovations Center 232
600 West Campus Drive
PO Box 27392
West Haven, CT 06516
Phone: 203-737-8670
Abbreviations: small open reading frame (sORF), sORF-encoded
polypeptides (SEPs), long noncoding RNA (lncRNA), untranslated region
(UTR), upstream ORF (uORF), overlapping uORF (o.uORF), downstream ORF
(dORF), alternative ORF (alt-ORF), ribosome profiling (Ribo-seq),
ribosome-protected fragment (RPF), translation initiation sequencing
(TI-seq), cryo-electron microscopy (cryo-EM), sarco/endoplasmic
reticulum (SR/ER) calcium ATPase (SERCA), ribosomal RNA (rRNA), short
linear interaction motifs (SLIMs), non-homologous end joining (NHEJ),
prefoldin-like (PFDL)
Keywords: sORF, Microprotein, Structure, Mass Spectrometry –
LC-MS/MS, Genome