2.4 Synthesis of DOX@RCNs
200mg RCNs were dispersed into 50mL deionized water and treated with
ultrasound for 20 min. After the ultrasonication, 40mg DOX was added to
the above-mentioned dispersions stirred slowly overnight. Then,
centrifugation was performed to eliminate the unadsorbed DOX. So far,
DOX@RCNs were prepared. The drug loading rate was obtained by measuring
the absorbance of the supernatant by UV-vis-NIR spectrophotometer. The
adsorption capacity was calculated by the following formula: