2.2 Characterization
The microstructure and morphology of the prepared samples were observed
by transmission electron microscopy (TEM, SU8220, Hitachi, Japan). The
surface groups of RCNs and DOX@RCNs were characterized by FT-IR
spectrometer (Spectrum 3™, PerkinElmer, America). The absorbance was
measured by UV-vis-NIR spectrophotometer (LAMBDA365, PerkinElmer,
America). The specific surface area was measured by surface comparator
(ASAP2460, Micromeritics,
America). The temperature of the solutions was recorded by a thermal
imaging camera (FLIR ONE Pro, Wilsonville, OR). Confocal microscopy
photos were taken by an Olympus BX51 fluorescence microscope (Olympus,
Tokyo, Japan).