Methods:
In ten animals, pre-ablation CTC between a novel large area focal (LAF)
ablation catheter and cardiac targets was evaluated using a custom local
impedance (LI) system, with guidelines established in previous pilot
studies using intracardiac echocardiography (ICE), electrogram
amplitude, and electroanatomic mapping (EAM) . Isolated ventricular
lesions and atrial lesion sets were created with varying amounts of CTC.
Treatment size and isolation of targeted structures were examined at
acute and chronic timepoints using EAM and histology.