Epidemiology:
GCTs are rare. According to a study at a single institution over 32
years, the overall incidence of granular cell tumors in surgical
specimens was 0.03% [6]. Some other studies suggest a prevalence of
1:617 among the screened population and 6.7:1000 cases in the total
clinical population [2,7]. GCTB can occur in both sexes, but is most
common in women, with a female: male proportion ratio ranging from 1.8
to 2.4 [8,9]. GCTB can occur in all age groups but is more common in
women in their 40s to 60s [6,10,11], although there have been cases
identified in patients as young as 14 years old [12,13]. It is also
more prevalent in African origin women, comprising about 60 to 70% of
the cases [11,14,15].