Introduction: Primary tracheal carcinoma is a rare and challenging disease that presents significant diagnostic and therapeutic difficulties. Delayed diagnosis due to misinterpretation of airway obstruction symptoms often leads to poorer prognoses for patients. This study aimed to explore the clinical manifestations and multidisciplinary treatment approaches for primary tracheal carcinoma in Bangladesh, with a focus on recent advancements in diagnosis and treatment. Methods: A retrospective observational study was conducted at Bangladesh Specialized Hospital Limited, involving patients aged over 30 who were diagnosed with tracheal carcinoma and underwent multidisciplinary treatment. Data were collected through patient interviews and medical record reviews. Descriptive and inferential statistical analyses were performed to examine demographic characteristics, histological variations, tumor locations, clinical signs and symptoms, treatment approaches, and outcomes. Results: Thirteen patients were included in the study, with a mean age of 49.15±10.50 years. The most common histological variations were invasive squamous cell carcinoma and adenoid cystic carcinoma. The upper trachea was the most prevalent tumor location. Dyspnea, cough, and hemoptysis were the most frequently reported symptoms. Surgical interventions, such as definitive surgery and apple coring surgery, were the primary treatment modalities. Multidisciplinary approaches including Adjuvant / definitive Radiotherapy resulted in a low rate of local recurrence, and patients with successful treatment had better survival outcomes. Conclusion: This study provides insights into the demographic and clinical characteristics of primary tracheal carcinoma in Bangladesh and highlights the importance of a multidisciplinary treatment approach. Further research with larger sample sizes is needed to validate these findings and improve diagnostic and therapeutic strategies for this rare malignancy.